Application of platelet-rich plasma in plastic surgery: clinical and in vitro evaluation.

Efficacy of Autologous Platelet-Rich Plasma (PRP) Activated By Thromboplastin-D on the Repair and Regeneration of Wounds in Dogs

Objective- To evaluate the effects of autologous platelet-rich plasma (PRP) on wound healing in dogs. Design- Experimental in-vivo study. Animals- 5 mix-breed male adult dogs. Procedures- Under general anesthesia, six 2 × 2-cm, full-thickness skin wounds were created on the back of dogs symmetrically. In each dog, three right side wounds were treated topically with 1.5 ml PRP jelly, whereas lef...

Management of Large Chronic Non-healing Wounds by Autogenous Platelet Rich Plasma and Reconstructive Surgery in Three Cats

Case Description- Three domestic short haired cats (2, 5 and 4 years of age) were presented to the Madras Veterinary College Teaching Hospital, with the history of large chronic, full thickness wounds on the right lateral cervical, left caudal forearm and right lateral thoracic region respectively. Etiology of the wounds was trauma in two cases and thermal burns in the third ca...

Temporal and Spatial Expression of TGF-b1 in the Early Phase of Patellar Tendon Healing after Application of Platelet Rich Plasma

   Background:The aim of this study is to find out the spatial and temporal expression of TGF-b1 during the tendon healing, after application of Platelet Rich Plasma (PRP). Methods: A patellar tendon defect model in rabbits was used for this purpose. 48 skeletally mature New Zealand White rabbits, weighing 3.5 kg, were used for this study. Equal numbers of animals from both groups were sacrific...

Comparison of the thickening of donor skin graft with conventional method (using vaseline gas) and platelet-rich plasma topical application

Background: Healing involves complex processes that are not yet fully known. The wound healing process consists of three stages. In all these stages, normal wound healing requires platelet activation, release of cytokines and growth hormones, and chemotaxis and cell differentiation. Platelets play a key role in homeostasis and wound healing and growth factor production of more than 30 carried o...

In vitro Evaluation of the antibacterial activity of Platelet-rich Plasma against Selected Oral and Periodontal Pathogens

Background: Despite the availability of a wide range of antibiotics, bacterial infections are among important challenges for the healthcare system. Therefore, the introduction of new antimicrobial preparations such as platelet-rich plasma (PRP) could be suggested theoretically as a preventive measure for bacterial infections. We aimed to evaluate the in vitro antibacterial activity of PRP again...

Use of Platelet Rich Plasma (PRP) and Hyaluronic Acid in Treatment of Extremity Gunshot Injuries: A Case Report